Found 10 matching trials
Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840
PHASE2The main objective of the study is to evaluate the change in liver copper (...
Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants
PHASE1This is a Phase 1, randomized, 2-period, 2-sequence, cross-over study desig...
Location
Clinical Trial Site
Early Access Program for ALXN1840 in Patients With Wilson Disease
N/AThis is an open-label, single-arm, multi-center EAP, designed to provide ea...
Status
No Longer Available
Location
Multiple Locations
Bioavailability Study of 2 Oral Formulations of ALXN1840
PHASE1The study will assess the relative bioavailability of 2 different formulati...
Location
Nucleus Network Pty Ltd.
A Study of the Cardiac Effects of ALXN1840 in Healthy Adults
PHASE1This study will evaluate the effect of a supratherapeutic dose of ALXN1840 ...
Location
PPD Development, LP
A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy Adults
PHASE1This was single-center, open-label, randomized, 3-period, 3-treatment, 6-se...
Location
Clinical Trial Site
A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults
PHASE1This was single-center, open-label, randomized, 3-period, 3-treatment, 6-se...
Location
Clinical Trial Site
Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Participants With Wilson Disease
PHASE3The study will evaluate the efficacy and safety of ALXN1840 (formerly calle...
Study of Oral ALXN1840 at 2 Dose Strengths in Healthy Adults
PHASE1To assess the relative bioavailability of ALXN1840 administered orally as a...
Location
Clinical Trial Site
Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants.
PHASE1This was a Phase 1, randomized, 2-period, 2-sequence, cross-over study desi...
Location
Clinical Trial Site